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Psychobiological Model of Pain

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Zeltzer, L.K., Bursch, B., & Walco, G. (1997). Pain responsiveness and chronic pain: A psychobiological perspective. Journal of Developmental & Behavioral Pediatrics, 18, 402-412.

This review is the first in a two-part series on chronic pain in infants, children, and adolescents. The first part focuses on the developmental psychobiology of chronic pain. That is, it reviews the neuroanatomy and neurophysiology of pain and the development of chronic pain. It also discusses theories of central pain perception and neuropsychological contributors to the development of chronic pain and pain-related disability.


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Bursch, B., & Walco, G., Zeltzer, L.K. (1998). Clinical assessment and management of chronic pain and pain-associated disability syndrome (PADS). Journal of Developmental & Behavioral Pediatrics, 19(1), 44-52.

This second article describes a biopsychosocial approach to the clinical assessment and management of chronic pain in children and adolescents.


Updated 7/2/2002